Limited proteolysis of the alpha-macroglobulin rat alpha 1-inhibitor-3. Implications for a domain structure
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چکیده
منابع مشابه
Limited proteolysis by macrophage elastase inactivates human alpha 1- proteinase inhibitor
Inflammatory mouse peritoneal macrophages secrete a metalloproteinase that is not inhibited by alpha 1-proteinase inhibitor. This proteinase, macrophage elastase, recognizes alpha 1-proteinase inhibitor with macrophage elastase does not involve a stable proteinase-inhibitor complex and results in the proteolytic removal of a peptide of apparent molecular weight 4,000-5,000 from the inhibitor. A...
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The alpha-macroglobulin proteinase inhibitors (alpha Ms) are a family of proteins with the unique ability to inhibit a broad spectrum of proteinases. Whereas monomeric, dimeric and tetrameric alpha Ms have been identified in vertebrates, all invertebrate alpha Ms characterized so far have been dimeric. This paper reports the isolation and characterization of a tetrameric alpha M from the tropic...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1991
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)99156-8